MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1
نویسندگان
چکیده
منابع مشابه
MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
MicroRNA (miR) are important regulators of gene expression, and aberrant miR expression has been linked to oncogenesis; however, little is understood about their contribution to lung tumorigenesis. Here, we determined that miR-31 is overexpressed in human lung adenocarcinoma and this overexpression independently correlates with decreased patient survival. We developed a transgenic mouse model t...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2017
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2017.63